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Stable angina

MedGen UID:
87401
•Concept ID:
C0340288
•
Disease or Syndrome
Synonyms: Angina Pectori, Stable; Angina Pectoris, Stable; Angina, Chronic Stable; Angina, Stable; Anginas, Chronic Stable; Anginas, Stable; Chronic Stable Angina; Chronic Stable Anginas; Pectori, Stable Angina; Pectoris, Stable Angina; Stable Angina; Stable Angina Pectori; Stable Angina Pectoris; Stable Angina, Chronic; Stable Anginas; Stable Anginas, Chronic
SNOMED CT: Stable angina (233819005)

Definition

Angina pectoris which has not recently changed in frequency, duration or intensity. Stable angina pectoris is relieved by rest or administration or oral, sublingual or transdermal antianginal medications. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStable angina

Professional guidelines

PubMed

Evolving Management Paradigm for Stable Ischemic Heart Disease Patients: JACC Review Topic of the Week.
Boden WE, Marzilli M, Crea F, Mancini GBJ, Weintraub WS, Taqueti VR, Pepine CJ, Escaned J, Al-Lamee R, Gowdak LHW, Berry C, Kaski JC; Chronic Myocardial Ischemic Syndromes Task Force
J Am Coll Cardiol 2023 Feb 7;81(5):505-514. doi: 10.1016/j.jacc.2022.08.814. PMID: 36725179Free PMC Article
Diagnosis and Management of Stable Angina: A Review.
Joshi PH, de Lemos JA
JAMA 2021 May 4;325(17):1765-1778. doi: 10.1001/jama.2021.1527. PMID: 33944871
Treatment of Angina: Where Are We?
Balla C, Pavasini R, Ferrari R
Cardiology 2018;140(1):52-67. Epub 2018 Jun 6 doi: 10.1159/000487936. PMID: 29874661

Recent clinical studies

Etiology

Diagnosis and Management of Stable Angina: A Review.
Joshi PH, de Lemos JA
JAMA 2021 May 4;325(17):1765-1778. doi: 10.1001/jama.2021.1527. PMID: 33944871
The ISCHEMIA Trial: "Stable Angina Cured".
King SB 3rd
Cardiovasc Revasc Med 2020 Feb;21(2):254-255. doi: 10.1016/j.carrev.2020.01.023. PMID: 32199667
WITHDRAWN: Trimetazidine for stable angina.
Ciapponi A, Pizarro R, Harrison J
Cochrane Database Syst Rev 2017 Mar 20;3(3):CD003614. doi: 10.1002/14651858.CD003614.pub3. PMID: 28319269Free PMC Article
Vasodilator Therapy: Nitrates and Nicorandil.
Tarkin JM, Kaski JC
Cardiovasc Drugs Ther 2016 Aug;30(4):367-378. doi: 10.1007/s10557-016-6668-z. PMID: 27311574Free PMC Article
Management of Patients With Stable Angina and Type 2 Diabetes.
Deedwania PC
Rev Cardiovasc Med 2015;16(2):105-13. doi: 10.3909/ricm0742. PMID: 26198557

Diagnosis

Diagnosis and Management of Stable Angina: A Review.
Joshi PH, de Lemos JA
JAMA 2021 May 4;325(17):1765-1778. doi: 10.1001/jama.2021.1527. PMID: 33944871
Management of Chronic Stable Angina.
Walters MA
Crit Care Nurs Clin North Am 2017 Dec;29(4):487-493. Epub 2017 Sep 29 doi: 10.1016/j.cnc.2017.08.008. PMID: 29107310
CLINICAL PRACTICE. Chronic Stable Angina.
Ohman EM
N Engl J Med 2016 Mar 24;374(12):1167-76. doi: 10.1056/NEJMcp1502240. PMID: 27007960
Management of Patients With Stable Angina and Type 2 Diabetes.
Deedwania PC
Rev Cardiovasc Med 2015;16(2):105-13. doi: 10.3909/ricm0742. PMID: 26198557
Stable angina pectoris.
Valgimigli M, Biscaglia S
Curr Atheroscler Rep 2014 Jul;16(7):422. doi: 10.1007/s11883-014-0422-4. PMID: 24838374

Therapy

WITHDRAWN: Trimetazidine for stable angina.
Ciapponi A, Pizarro R, Harrison J
Cochrane Database Syst Rev 2017 Mar 20;3(3):CD003614. doi: 10.1002/14651858.CD003614.pub3. PMID: 28319269Free PMC Article
Inappropriate sinus tachycardia: focus on ivabradine.
Abed HS, Fulcher JR, Kilborn MJ, Keech AC
Intern Med J 2016 Aug;46(8):875-83. doi: 10.1111/imj.13093. PMID: 27059112
Colchicine for cardiovascular medicine.
Imazio M, Gaita F
Future Cardiol 2016 Jan;12(1):9-16. Epub 2015 Dec 3 doi: 10.2217/fca.15.59. PMID: 26632860
Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients.
Antithrombotic Trialists' Collaboration
BMJ 2002 Jan 12;324(7329):71-86. doi: 10.1136/bmj.324.7329.71. PMID: 11786451Free PMC Article
Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration.
Yusuf S, Zucker D, Peduzzi P, Fisher LD, Takaro T, Kennedy JW, Davis K, Killip T, Passamani E, Norris R
Lancet 1994 Aug 27;344(8922):563-70. doi: 10.1016/s0140-6736(94)91963-1. PMID: 7914958

Prognosis

Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1·9 million people.
Shah AD, Langenberg C, Rapsomaniki E, Denaxas S, Pujades-Rodriguez M, Gale CP, Deanfield J, Smeeth L, Timmis A, Hemingway H
Lancet Diabetes Endocrinol 2015 Feb;3(2):105-13. Epub 2014 Nov 11 doi: 10.1016/S2213-8587(14)70219-0. PMID: 25466521Free PMC Article
Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people.
Rapsomaniki E, Timmis A, George J, Pujades-Rodriguez M, Shah AD, Denaxas S, White IR, Caulfield MJ, Deanfield JE, Smeeth L, Williams B, Hingorani A, Hemingway H
Lancet 2014 May 31;383(9932):1899-911. doi: 10.1016/S0140-6736(14)60685-1. PMID: 24881994Free PMC Article
Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease.
Carson JL, Brooks MM, Abbott JD, Chaitman B, Kelsey SF, Triulzi DJ, Srinivas V, Menegus MA, Marroquin OC, Rao SV, Noveck H, Passano E, Hardison RM, Smitherman T, Vagaonescu T, Wimmer NJ, Williams DO
Am Heart J 2013 Jun;165(6):964-971.e1. Epub 2013 Apr 8 doi: 10.1016/j.ahj.2013.03.001. PMID: 23708168Free PMC Article
Angina (chronic stable).
O'Toole L
BMJ Clin Evid 2008 Oct 1;2008 PMID: 19445795Free PMC Article
Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration.
Yusuf S, Zucker D, Peduzzi P, Fisher LD, Takaro T, Kennedy JW, Davis K, Killip T, Passamani E, Norris R
Lancet 1994 Aug 27;344(8922):563-70. doi: 10.1016/s0140-6736(94)91963-1. PMID: 7914958

Clinical prediction guides

Coronary angiography-derived contrast fractional flow reserve.
Gong Y, Zheng B, Yi T, Yang F, Hong T, Liu Z, Huo Y, Li J, Huo Y
Catheter Cardiovasc Interv 2022 Feb;99(3):763-771. Epub 2021 Feb 15 doi: 10.1002/ccd.29558. PMID: 33590679
Low-Attenuation Noncalcified Plaque on Coronary Computed Tomography Angiography Predicts Myocardial Infarction: Results From the Multicenter SCOT-HEART Trial (Scottish Computed Tomography of the HEART).
Williams MC, Kwiecinski J, Doris M, McElhinney P, D'Souza MS, Cadet S, Adamson PD, Moss AJ, Alam S, Hunter A, Shah ASV, Mills NL, Pawade T, Wang C, Weir McCall J, Bonnici-Mallia M, Murrills C, Roditi G, van Beek EJR, Shaw LJ, Nicol ED, Berman DS, Slomka PJ, Newby DE, Dweck MR, Dey D
Circulation 2020 May 5;141(18):1452-1462. Epub 2020 Mar 16 doi: 10.1161/CIRCULATIONAHA.119.044720. PMID: 32174130Free PMC Article
1-Year Outcomes of Angina Management Guided by Invasive Coronary Function Testing (CorMicA).
Ford TJ, Stanley B, Sidik N, Good R, Rocchiccioli P, McEntegart M, Watkins S, Eteiba H, Shaukat A, Lindsay M, Robertson K, Hood S, McGeoch R, McDade R, Yii E, McCartney P, Corcoran D, Collison D, Rush C, Sattar N, McConnachie A, Touyz RM, Oldroyd KG, Berry C
JACC Cardiovasc Interv 2020 Jan 13;13(1):33-45. Epub 2019 Nov 11 doi: 10.1016/j.jcin.2019.11.001. PMID: 31709984Free PMC Article
Vasospastic angina: A literature review of current evidence.
Picard F, Sayah N, Spagnoli V, Adjedj J, Varenne O
Arch Cardiovasc Dis 2019 Jan;112(1):44-55. Epub 2018 Sep 7 doi: 10.1016/j.acvd.2018.08.002. PMID: 30197243
Fractional flow reserve: a clinical perspective.
Corcoran D, Hennigan B, Berry C
Int J Cardiovasc Imaging 2017 Jul;33(7):961-974. Epub 2017 Jun 2 doi: 10.1007/s10554-017-1159-2. PMID: 28577046Free PMC Article

Recent systematic reviews

Cost-utility of Ranolazine for Chronic Stable Angina Pectoris: Systematic Review and Meta-analysis.
Ayyasamy L, Bagepally BS
Clin Ther 2023 May;45(5):458-465. Epub 2023 Apr 21 doi: 10.1016/j.clinthera.2023.04.004. PMID: 37087299
The performance of non-invasive tests to rule-in and rule-out significant coronary artery stenosis in patients with stable angina: a meta-analysis focused on post-test disease probability.
Knuuti J, Ballo H, Juarez-Orozco LE, Saraste A, Kolh P, Rutjes AWS, Jüni P, Windecker S, Bax JJ, Wijns W
Eur Heart J 2018 Sep 14;39(35):3322-3330. doi: 10.1093/eurheartj/ehy267. PMID: 29850808
WITHDRAWN: Trimetazidine for stable angina.
Ciapponi A, Pizarro R, Harrison J
Cochrane Database Syst Rev 2017 Mar 20;3(3):CD003614. doi: 10.1002/14651858.CD003614.pub3. PMID: 28319269Free PMC Article
Exercise-based cardiac rehabilitation for coronary heart disease.
Anderson L, Thompson DR, Oldridge N, Zwisler AD, Rees K, Martin N, Taylor RS
Cochrane Database Syst Rev 2016 Jan 5;2016(1):CD001800. doi: 10.1002/14651858.CD001800.pub3. PMID: 26730878Free PMC Article
Angina (chronic stable).
O'Toole L
BMJ Clin Evid 2008 Oct 1;2008 PMID: 19445795Free PMC Article

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